摘要：
   目的：介绍内镜经鼻脑脊液鼻漏修补术的外科技术。
   方法：2003年10月到2008年12月诊治脑脊液鼻漏病人38例，38例行内镜经鼻手术，其中外伤性脑脊液鼻漏12例，自发性10例，其它原因16例。8例病人行术中荧光示踪检查。
   结果：术后随访6月~3年，1次手术成功率为94.7%。2次及3次手术成功各1例，术后脑膜炎及梗阻性脑积水各1例。
   结论：内镜经鼻脑脊液鼻漏修补术成功率高，创伤小，应作为首选治疗方法；漏口定位及处理、适宜的外科修补技术及术后处理是手术成功的关键。
关键词：脑脊液鼻漏，颅底，内镜，手术，经鼻手术
Endoscopic endonasal approaches for repair of cerebrospinal fluid rhinorrhea
Abstract: Objective: To describe surgical experience in repair of cerebrospinal fluid (CSF) rhinorrhea treated by endoscopic transnasal approaches. Methods: Between October 2003 and December 2008,  38 patients with CSF rhinorrhea were treated. Endoscopic endonasal approaches and surgical techniques in the repair of CSF leaks are reviewed in the series of 38 patients included 12 patients with traumatic CSF leaks, 10 patients with spontaneous CSF leaks, and 16patients with other reason. Results: Follow-up 6 months to 3 years postoperative, successful rate at first attempt was 94.7%. 1 patient needed a Second surgical repair and one patient a third surgical repair. The complication included meningitis and obstruction hydrocephalus in two patients. Conclusions: The endoscopic endonasal approaches is first choice for repair of CSF leak for its minimal invasive injure and high successful rate. Leak site identification, site preparation, accurate graft placement and postoperative management are critical to achieve a high level of success.
Keywords: Cerebrospinal fluid leaks, Cranium base, Surgery, Endonasal surgery, Endoscope